Subjects
- The algorithm was derived from 475 Chinese full-term neonates with CSF pleocytosis (defined as a CSF WBC ≥10 ×106 cells/L) and with no antibiotic pretreatment within 72 hours of their diagnostic lumber punctures.
How to use
- Enter CSF protein level (< 1650 mg/L or ≥ 1650 mg/L), CSF absolute neutrophil count (< 84×106 cells/L or ≥ 84×106 cells/L), and Positive CSF Gram stain (Yes or No) , then the risk stratification are calculated automatically as not low risk and very low risk.
- If a patient is at not low risk, he or she is suggested to use prolonged broad-spectrum antibiotic.
- If at very low risk, he or she is not suggested to use prolonged broad-spectrum antibiotic.
Note
- Patients older than 28 days or with antibiotic pretreatment before diagnostic lumber puncture or CSF red blood >1000×106 cells/L are not applicable to this calculator.
Wang et al. An improved clinical prediction rule for identifying neonatal bacterial meningitis in the neonatal intensive care unit.
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